If concomitant use is warranted, since respiratory depression might be better than normally anticipated, decrease the dosage of acetaminophen and codeine phosphate tablets and/or the muscle relaxant as required.
Keep away from the use of acetaminophen and codeine phosphate tablets in adolescents 12 to eighteen many years of age who produce other chance aspects which will raise their sensitivity for the respiratory depressant effects of codeine Except the benefits outweigh the risks.
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When getting acetaminophen and codeine phosphate tablets: Do not improve your dose. Take acetaminophen and codeine phosphate tablets accurately as prescribed by your Health care service provider. Use the bottom dose probable for that shortest time necessary. For acute (shorter-term) soreness, you may only have to take acetaminophen and codeine phosphate tablets for a couple of days.
Hepatotoxicity Acetaminophen continues to be linked to situations of acute liver failure, occasionally leading to liver transplant and Loss of life.
You'll have some acetaminophen and codeine phosphate tablets left around that you didn't use. See disposal facts at the bottom of this area for Instructions regarding how to properly toss away (get rid of) your unused acetaminophen and codeine phosphate tablets.
The excessive ingestion of acetaminophen could possibly be intentional to cause self-damage or check here unintentional as individuals try and get much more ache relief or unknowingly choose other acetaminophen-made up of merchandise.
Parenteral drug abuse is usually related to transmission of infectious illnesses including read more hepatitis and HIV.
It's not a whole list of probable get more info Uncomfortable side effects. In the event you discover other outcomes more info not mentioned higher than, Get in touch with your health practitioner or pharmacist.
Consume six to 8 full Eyeglasses of water day by day that will help prevent constipation if you are using this drugs. Tend not to make use of a stool softener (laxative) without 1st asking your health care provider.
Educate clients and caregivers on how to acknowledge respiratory depression and emphasize the necessity of calling 911 or acquiring emergency clinical help straight away during the event of a regarded or suspected overdose (see WARNINGS, Lifestyle-Threatening Respiratory Melancholy).
Acetaminophen and codeine phosphate tablets, like other opioids, can be diverted for nonmedical use into illicit channels of distribution.
Consider prescribing naloxone, dependant on the affected individual’s chance aspects for overdose, like concomitant use of other CNS depressants, a history of opioid use ailment, or prior opioid overdose. The existence of hazard things for overdose mustn't stop click here the appropriate management of ache in almost any offered patient. Also take into consideration prescribing naloxone If your affected person has domestic members (such as little ones) or other close contacts at risk for accidental ingestion or overdose.
Opioid Analgesic REMS: To make certain that the many benefits of opioid analgesics outweigh the risks of addiction, abuse, and misuse, a REMS is needed for these goods. Below the necessities on the REMS, drug companies with authorised opioid analgesic goods have to make REMS-compliant education programs accessible to healthcare vendors.